
You will be expected to maintain accurate electronic records of experiments and ensure that your own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal and external regulations and standards. You will present findings in multiple group and departmental meetings. You will also stay up to date with new technologies and assay formats for evaluation of human immune function. You will stay up to date with the latest discoveries in immunology and oncology, share your expertise both within and beyond the IO Discovery group.

You will be involved in designing and executing small scale screens to identify potential immunomodulatory drug candidates. Working within the IO Discovery team, you will apply your technical and scientific experience to design, conduct, and analyze in vitro experiments using primary human immune cells for enhancing anti-tumor immune responses. Furthermore, the individual will be expected to work in a team and in a cross-functional matrix environment as the project advances through the drug discovery pipeline. We are seeking a self-motivated and passionate individual with a strong lab/practical background in in vitro human immunology who is passionate about novel approaches to drug discovery. flow cytometry) for the analysis of human immune function is crucial for this role. This is primarily a bench scientist role and proficiency in techniques (e.g. As member of IO Discovery group, you will design, conduct, and analyze in vitro experiments to assess novel immunological mechanisms that can be exploited to enhance anti-tumor immunity. Our research has a broad scope involving innate and adaptive immune cells and exploring dysfunction in metabolic pathways, antigen presentation, and antigen receptor signaling. This department is researching novel immune mechanisms with the aim to develop next generation therapies that reverse the immunosuppressive tumor microenvironment. The IO Discovery department within ICC (Immuno-Oncology, Immune Circuits & Engagers and Cell Therapy) of Early Oncology R&D at AstraZeneca develops immunotherapies targeting cancer that boost the immune responses in tumors. We are seeking a highly motivated Senior Scientist in the Immuno-Oncology Discovery team with strong scientific and broad technical expertise in human immunology to join our team in Gaithersburg, MD. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life.ĪstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. We’re passionate about the potential of science to address the unmet needs of patients around the world.


Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. At AstraZeneca, we turn ideas into life changing medicines.
